Effect of Magnesium Sulfate Given for Neuroprotection Before Preterm Birth<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>
نویسندگان
چکیده
منابع مشابه
Effect of magnesium sulfate given for neuroprotection before preterm birth: a randomized controlled trial.
CONTEXT Prenatal magnesium sulfate may reduce the risk of cerebral palsy or death in very preterm infants. OBJECTIVE To determine the effectiveness of magnesium sulfate given for neuroprotection to women at risk of preterm birth before 30 weeks' gestation in preventing pediatric mortality and cerebral palsy. DESIGN, SETTING, AND PATIENTS Randomized controlled trial at 16 tertiary hospitals ...
متن کاملAntenatal magnesium sulfate for neuroprotection before preterm birth?
Preterm infants are at increased risk for serious, lifelong neurologic abnormalities such as cerebral palsy.1,2 As the survival of preterm infants has improved with advances in perinatal care,2 the occurrence of cerebral palsy has increased further, since infants who would previously have died now survive with their cerebral pathology. Currently, more than 30% of children with cerebral palsy ar...
متن کاملPatient safety checklist No. 7: magnesium sulfate before anticipated preterm birth for neuroprotection.
Numerous large clinical studies have evaluated the evidence regarding magnesium sulfate, neuroprotection, and preterm births. The Committee on Obstetric Practice and the Society for Maternal-Fetal Medicine recognize that none of the individual studies found a benefit with regard to their primary outcome. However, the available evidence suggests that magnesium sulfate given before anticipated ea...
متن کاملA PROSPECTIVE, RANDOMIZED, CONTROLLED TRIAL OF HIGH AND LOW DOSES OF MAGNESIUM SULFATE FOR ACUTE TOCOLYSIS
At the present, many drugs are used for inhibition of uterine contractions, but the proportions of preterm labors are increasing. Although magnesium sulfate is the most commonly prescribed parenteral tocolytic agent, but its optimal use has yet to be delineated. In this study a high-dose protocol for magnesium sulfate tocolytic therapy was compared with a low-dose regimen. One-hundred patie...
متن کاملMagnesium sulfate for prevention of preterm birth.
Practice Pointers Preterm birth, defined as occurring before 37 weeks of gestation, is the leading cause of neonatal death and is associated with several shortand long-term infant morbidities. Tocolytics, agents that inhibit uterine contractions, are commonly used to prevent or delay preterm birth. Magnesium sulfate is one of the most commonly used tocolytics in the United States.1 An earlier p...
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ژورنال
عنوان ژورنال: JAMA
سال: 2003
ISSN: 0098-7484
DOI: 10.1001/jama.290.20.2669